David Bryce

David A. Bryce is currently a Ph.D candidate at the University of Utah, working in the Joel M. Harris research group. David received a Bachelor’s of Science degree in chemistry from Central Washington University in 2012. During his undergraduate studies, David worked with Prof. Dion Rivera, utilizing ATRFTIR methods for investigating polyelectrolyte adsorption to oxide films. After graduating, David worked as a post bachelor’s research assistant at Pacific Northwest National Lab, developing infrared spectroscopic methodology for in situ study of the partitioning of contaminants between water and supercritical CO2. Following this post bachelor’s appointment David moved to the University of Utah to pursue a graduate degree in analytical chemistry, working for Joel Harris. At present, David is the Society for Applied Spectroscopy student representative. David’s work in the Harris research group has focused on developing and utilizing confocal Raman microscopy methods for analysis carried out within individual chromatographic particles. David’s work in the Harris group initially focused on the measurement and modeling of accumulation kinetics of polyaromatic hydrocarbons in reversed-phase chromatographic silica. More recent work has focused on the preparation and characterization of supported phospholipid bilayers throughout the pore-network of chromatographic silica particles, and use of these pore-confined bilayers for label-free confocal Raman microscopy experiments to detect membrane partitioning of small molecules, specific protein binding to membrane localized ligands, and detection of signaling peptide accumulation. This work provides both quantitative and structural information about these molecular interactions with phospholipid membranes.