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Resonant Cell Laser-Based Photoacoustic Densitometer for Thin-Layer Chromatography

Volume 42, Number 7 (Oct. 1988) Page 1228-1231

Kawazumi, Hirofumi; Yeung, Edward S.

Photoacoustic spectroscopy was applied to the in situ densitometry of thin-layer chromatographic plates. Fast laser-scanning detection with signal enhancement was demonstrated at a resonant frequency of the cell. The use of phase difference between signal and background provided higher signal-to-noise ratios. Detection limit for Orange G was 170 pg, and the analytical curve was linear over three orders of magnitude.