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Reduction of Mass-Dependent Interferences in Inductively Coupled Plasma-Mass Spectrometry by Using Flow-Injection Analysis

Volume 43, Number 8 (Dec. 1989) Page 1330-1333

Vickers, George H.; Ross, Barbara S.; Hieftje, Gary M.


The use of flow-injection analysis to reduce mass-dependent interferences in inductively coupled plasma-mass spectrometry has been assessed. Results are presented which demonstrate nearly complete elimination of analyte-signal suppression under operating conditions where dispersion (D) is approximately 25. Furthermore, results obtained with flow-injection analysis exhibit greater precision, take less time, and suffer only a 40% reduction in sensitivity, compared to continuous-flow analysis.