The following is an abstract for the selected article. A PDF download of the full text of this article is available here. Members may download full texts at no charge. Non-members may be charged a small fee for certain articles.
Evolving Factor Analysis for Frequency-Domain Lifetime Resolution of Fluorescence Spectra
Volume 46, Number 1 (Jan. 1992) Page 28-33
Millican, David W.; McGown, Linda B.
Evolving factor analysis (EFA) is a new approach to the resolution of individual component spectra on the basis of fluorescence lifetime differences. Phase-resolved fluorescence spectra collected at several excitation modulation frequencies are well suited to EFA resolution because the frequency-response curve of phase-resolved intensity for each lifetime component has a single, unique maximum. Unlike other self-modeling spectral matrix resolution methods, EFA has no fundamental limitation upon the number of components that can be resolved. In this work, the resolution of two-component and three-component mixtures of polycyclic aromatic hydrocarbons is demonstrated.