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Identification of Xylene Isomers in High-Pressure Liquid Chromatography Eluates by Raman Spectroscopy

Volume 51, Number 11 (Nov. 1997) Page 1644-1647

Steinert, Roland; Bettermann, Hans; Kleinermanns, Karl

This contribution presents a combination of high-pressure liquid chromatography (HPLC) with a Raman spectrometer. With this approach, we have identified both isomer m-xylene and isomer p- xylene in solution at concentrations down to 10 -5 mol/L. The setup was developed to analyze compounds that cannot be separated by using standard HPLC techniques.