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Determination of Silicone in Breast Tissue by Graphite Furnace Continuum Source Atomic Absorption Spectrometry

Volume 47, Number 10 (Oct. 1993) Page 1577-1579

Wichems, D.N.; Calloway, Clifton P.; Fernando, Reshan; Jones, Bradley T.; Morykwas, Michael J.


A method has been developed for the determination of silicone in breast tissue samples using a graphite furnace continuum source atomic absorption spectrometer. Silicone was measured as Si present in a heptane extract of the dried tissue samples. Thirty tissue samples were examined from 16 women having silicone gel-filled breast implants. Concentrations of Si in the dried tissue samples ranged from below the method detection limit of 3 ppm, to 6%.